The paper examines and describes country and firm level trends as related to environmental sustainability in selected Latin American, Middle East & North Africa (MENA) countries. Composite indexes such as the Human Development Index, the Ecological Footprint Index and Biocapacity ratios provide a snapshot of a country’s environmental sustainability level over time. Firm level sustainability is based on a qualitative analysis of companies using the Global Reporting Initiative (GRI) framework and UN Global Compact participation. At the national level, all the selected countries, except Argentina, do not meet the environmental sustainability criteria. However, despite the lack of integration between initiatives proposed by different institutions, firm level sustainability trends are positive and encouraging, albeit not sufficient. The need of a concerted effort to align different organizations and institutions regarding sustainability initiatives in the studied regions is apparent. The synergies between these initiatives are also explored.