This article aims to describe the impacts on project management and the quality of hospital services with the implementation of a Project Management Office (PMO) in a private hospital. To this end, non-participant observation, semi-structured interviews with professionals involved in the implementation of the PMO and document analysis were used. The interviews were conducted with five employees and analysed through content analysis. The results showed that the hospital faced challenges such as lack of project organization, centralization of information, and a systematic approach to projects and indicators. Communication between teams was fragmented, resulting in divergent information and difficulties in defining strategic objectives. The PMO was understood as indispensable to face emerging challenges, innovate and ensure efficient project management in the hospital context, promoting a culture of transparency, efficiency and collaboration. As a contribution, it is noted that more effective project management can improve the quality of healthcare, optimizing the use of resources and make transparent healthcare policies. This results in a more systematic and integrated approach, increasing the efficiency and effectiveness of hospital operations. In this sense, this study observed how the PMO can create data management tools, better definition and understanding of strategic and operational indicators, as well as improve the effective participation of all areas involved in the projects by promoting structured and effective communication.